Coated Colloidal Silver Mechanism of Action
Not very many are aware that colloidal silver was essential in medicine for its antibacterial and antiseptic properties. It was widely used long before antibiotics and chemical-based germicides were invented.
However, the properties of silver change depending on form and particle size. Silver nitrate, for instance, can accumulate in the body and lead to toxicity. Prior to the 1900s, practitioners were aware that silver in its colloidal form delivers the most effective bacteria-fighting activity. Coated Colloidal Silver was created along these observations.
What is Coated Colloidal Silver?
Colloidal Silver consists of silver nanoparticles that are between 1 and 100 nanometers in size. Silver particles this minute take on properties that are considered unique for colloids which, according to Voyutsky (in Baranowski) [1], can be characterized as follows:
- Heterogeneous. It consists of two components that will never mix which, in this case, are silver and water.
- Multiphasic. Colloids exist in non-exclusive phases. It is always in a grey area, for instance, between solid and liquid, or between liquid and gas.
- Insoluble. Colloids will not dissolve in any type of solution.
These properties make colloidal silver special. Add to that, the fact that it will never lose these properties when combined with any other systems or solutions gives it extraordinary advantages above other forms of silver.
Therefore, coated colloidal silver exhibits higher efficacy, better stability, and an outstanding safety profile compared to plain colloidal silver preparations.
5 ml
83 drops
20000 PPM
15 ml
250 drops
20000 PPM
30 ml
500 drops
20000 PPM
Mechanism of Action: How Coated Colloidal Silver Works
As soon as coated colloidal silver enters the body, it starts releasing silver ions gradually and constantly. It does so for a period of time while keeping its structural integrity intact and without being absorbed by or dissolved into the system. The problem with uncoated colloidal silver is that it clumps very easily and gets trapped in body tissues over time. There is no physiological reason to maintain silver metal in the body indefinitely.
Unlike plain colloidal silver, the coating provides a regulated timing of the release of silver ions when introduced inside the body. This way, it does not overwhelm the system. Moreover, this controlled release mechanism makes coated silver non-toxic.
Meanwhile, it targets harmful bacteria in the system and this is what happens:
- First, silver nanoparticles almost immediately attack the bacteria’s cell membrane, successfully penetrating it not long after it makes contact.
In one study, researchers noted a considerable break in the bacterial membrane just minutes after these were exposed to silver ions. In about 90 minutes [2], researchers observed a significant reduction in the population of Staphylococcus aureus and Escherichia coli, the bacterial strains used in this study.
Silver nanoparticles can enter a bacteria’s membrane quickly on contact.
- Second, infectious bacteria experience intense oxidative stress as soon as positive silver ions are able to penetrate their membrane.
A study of bacterial causes of UTI (urinary tract infection) demonstrated the process and showed that by inducing the production of free radicals [3], bacterial cells undergo a series of chain reactions. In time, this results in a significant loss of an effective supply of oxygen and nourishment, forcing bacteria to operate in a closed system environment.
When silver ions enter a bacteria’s cell membrane, it disrupts its function and causes a strong oxidative reaction.
- Third, multiple reactions with amino acids at the sub-cellular levels further damage bacteria. This, accompanied by the loss of antioxidant enzymes that protect the bacteria causes growth and reproduction to halt [4]. The cytotoxic and genotoxic effect of AgNPs eventually causes the bacteria to die, making a treatment from infection successful.
Take note that the exact mechanism of colloidal silver against harmful bacteria has yet to be explained in full. These accounts are based on the best available information from the research community.
Coated Colloidal Silver vs. Colloidal Silver
While any colloidal silver preparation may be capable of delivering the mechanism of action against harmful microorganisms described in the previous section, many will deliver sub-optimal performance. As simple as it may sound, one of the primary features that can make a world of difference is whether or not a colloidal silver preparation is coated.
There are two main reasons why coated colloidal silver will always be the better choice compared to plain, uncoated colloidal silver:
- Coated Silver contains a very high concentration of silver nanoparticles for every drop which is estimated to be 20 000ppm. That equates to higher levels of silver nanoparticles than any other brand available in the market today.
- Coated Silver nanoparticles are capable of regulating and timing the release of AgNP+ ions in the body. It’s formulated with smart nanotechnology that is able to detect the level of silver ions in the body and adjust subsequent releases accordingly.
This mechanism addresses concerns of introducing an oversupply of silver ions which can lead to adverse effects, including cytotoxicity in healthy cells. This is far from the scenario that can be derived from using ionic silver. Learn more about the differences between colloidal vs ionic silver.
- The body can tolerate coated silver nanoparticles. Coated colloidal silver can safely pass through the body and be effectively eliminated via normal excretory pathways.
That means, coated colloidal silver will not result in the deposition of silver in the body which is the primary cause of argyria. This condition causes the body or a part of the body (the cornea in the case of argyrosis) to turn into a bluish-grey appearance. Although there are no toxic effects [5] detected among people exhibiting this condition, its appearance may cause psychological distress in some people.
Why Coated Silver is Good for Your Body
Colloidal silver works as an antibacterial, one of several other benefits that modern science and history of use in medical settings have demonstrated time and again.
Noble Elements LLC is the only manufacturer of coated colloidal silver with an approved patent. It is the most efficient, stable, safe, and economical choice compared to other brands of colloidal silver available in the market today. Here’s why:
- Coated Silver delivers 10nm of coated silver nanoparticles, whereas the top-selling brands are delivering silver nanoparticles greater than 10nm [6]. Smaller and finer molecules are more potent than larger, coarser particles.
- Coated Silver delivers uniformly sized silver nanoparticles. That equates to greater stability and better consistency compared to its competitors.
- Coated Silver delivers close to 20 000ppm per drop, so much more than any of its top competitors normally delivering just 250ppm or less for the same amount. That means you get more value for your money when you buy a slightly more expensive bottle of concentrated Coated Silver than buying a product that appears to cost less but has been watered down.
By choosing Coated Silver, you can save as much as $206.99 for every gallon containing 10ppm of nanosilver. 10ppm is the ideal concentration for the therapeutic benefits of colloidal silver to be harnessed.
Coated Silver is available on this website. You may also get it from amazon.com or from our partners, David Avocado Wolfe, Cymbiotika, and other partner distributors online and in-store.
“These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.”
- Vuyutsky SS in Baranowski Z. (1995). “Colloidal Silver: The Natural Antibiotic Alternative”. Healing Wisdom Publications.
- Jung WK, Koo HC, Kim KW, Shin S, Kim SH, Park YH. Antibacterial activity and mechanism of action of the silver ion in Staphylococcus aureus and Escherichia coli. Appl Environ Microbiol. 2008 Apr;74(7):2171-8. doi: 10.1128/AEM.02001-07. Epub 2008 Feb 1. PMID: 18245232; PMCID: PMC2292600. Access Date: 8 Feb 2021.
- Morones-Ramirez JR, Winkler JA, Spina CS, Collins JJ. “Silver enhances antibiotic activity against gram-negative bacteria”. Sci Transl Med. 2013 Jun 19;5(190):190ra81. doi: 10.1126/scitranslmed.3006276. PMID: 23785037; PMCID: PMC3771099. Access Date: 8 Feb 2021
- Monteiro DR, Gorup LF, Takamiya AS, de Camargo ER, Filho AC, Barbosa DB. “Silver distribution and release from an antimicrobial denture base resin containing silver colloidal nanoparticles”. J Prosthodont. 2012 Jan;21(1):7-15. doi: 10.1111/j.1532-849X.2011.00772.x. Epub 2011 Nov 2. PMID: 22050139.
- Lansdown, Alan. (2010). “A Pharmacological and Toxicological Profile of Silver as an Antimicrobial Agent in Medical Devices. Advances in pharmacological sciences”. 2010. 910686. 10.1155/2010/910686. Access Date: 15 Feb 2021.
- Kumar A, Goia DV. Comparative Analysis of Commercial Colloidal Silver Products. Int J Nanomedicine. 2020;15:10425-10434. https://doi.org/10.2147/IJN.S287730 Access Date: 8 Feb 2021.
